Nkhani - Kugwiritsa Ntchito Zinc Oxid Wamba Pochiza Matenda Otsegula M'mimba a Ana A Nkhumba

Ine.

Zinki okusayidi, yomwe imadziwika kuti zinc white, ndi amphotericzinki okusayidiChomwe sichisungunuka m'madzi koma chimasungunuka mu asidi ndi alkali wamphamvu. Fomula yake ya mankhwala ndi ZnO, kulemera kwa mamolekyu ndi 81.37, nambala ya CAS ndi 1314-13-2, malo osungunuka ndi 1975℃ (kuwonongeka), malo owira ndi 2360℃, ndipo sichisungunuka m'madzi. Chimagwiritsidwa ntchito kwambiri m'magawo opitilira 20 monga mapulasitiki, zinthu zopangidwa ndi silicate, rabara yopangidwa, mafuta odzola, utoto ndi zokutira, mafuta odzola, zomatira, chakudya, mabatire, zoletsa moto,ndi zina zotero.

Chithunzi 1Zinki okusayidichitsanzo

III. Mavuto a kutsegula m'mimba mwa ana a nkhumba olekanitsidwa ndi kufunika kwazinki okusayidi

Kusiya kuyamwa ndi vuto lalikulu pa moyo wa mwana wa nkhumba. Mavuto monga kufooka kwa ntchito yotchinga matumbo, kusakwanira kutulutsa ma enzymes am'mimba, komanso kusalinganika kwa zomera nthawi zambiri kumabweretsa kutsegula m'mimba (PWD) pambuyo posiya kuyamwa, zomwe zimawopseza kwambiri kukula ndi ubwino wa kuswana kwa ana a nkhumba.zinki okusayidiPopeza kuti anapezeka kuti ali ndi zotsatirapo zazikulu zotsutsana ndi kutsegula m'mimba m'zaka za m'ma 1980, wakhala "muyezo wagolide" wa makampani opanga ziweto padziko lonse lapansi kuti athane ndi anthu olumala. Kafukufuku wasonyeza kuti kuwonjezera 2500-3000 mg/kgzinki okusayidiKuchepetsa kuchuluka kwa matenda otsegula m'mimba ndi 40%-60%, pomwe kumawonjezera kulemera kwa tsiku ndi tsiku ndi 10%-15%. Phindu lake lalikulu ndi kukhazikika mwachangu m'matumbo kudzera munjira zosiyanasiyana, kupereka chitetezo chofunikira kwambiri kwa ana a nkhumba.

Mavuto a kutsegula m'mimba mwa ana a nkhumba olekanitsidwa ndi kufunika kwa zinc oxide kuchipatala

IV.Njira yogwirira ntchito yazinki okusayidimotsutsana ndi kutsegula m'mimba

1)Kulimbitsa chotchinga cha m'mimba

Zinki okusayidiZimathandizira kuchulukana kwa maselo a epithelial m'matumbo, zimawonjezera kwambiri chiŵerengero cha kutalika kwa matumbo a villus ndi kuya kwa crypt, zimathandizira kuti pamwamba pa thupi pakhale michere, komanso nthawi yomweyo zimawonjezera kufalikira kwa mapuloteni olimba (Occludin, ZO-1), zimachepetsa kulowa kwa mucosal m'matumbo, ndikuletsa kulowetsedwa kwa tizilombo toyambitsa matenda. Zimateteza ntchito yotchinga mucosal m'matumbo, zimawonjezera mphamvu ya mabakiteriya a ana a nkhumba, komanso zimachepetsa kutsegula m'mimba.

Chithunzi 2Zotsatira za milingo yosiyanasiyana yazinki okusayidiza mawonekedwe a m'mimba mwa ana a nkhumba

Chithunzi 3 Zotsatira za kuchuluka kosiyanasiyana kwa zinc oxide pa mapuloteni ogwirizana m'matumbo mwa ana a nkhumba

Chithunzi 3Zotsatira za milingo yosiyanasiyana yazinki okusayidipa mapuloteni omangira matumbo mwa ana a nkhumba

2)Kuwongolera bwino kwa tizilombo toyambitsa matenda m'matumbo

Zinki okusayidiimapanga hydrogen peroxide m'matumbo, yomwe ndi chinthu chofunikira kwambiri pa ntchito ya antibacterial yazinki okusayidiMlingo wokwerazinki okusayidiimaletsa mwachindunji kuchulukana kwa mabakiteriya opatsirana monga Escherichia coli ndi Salmonella mwa kutulutsa mitundu ya okosijeni yogwira ntchito (ROS), pomwe ikulimbikitsa kufalikira kwa mabakiteriya opindulitsa monga Lactobacillus.

Chithunzi 4Zotsatira za zakudyazinki okusayidipa tizilombo toyambitsa matenda a cecal mwa ana a nkhumba

3) Zinc wambiri amalimbikitsa kukula kwa ana a nkhumba

Kupsinjika kwa kuyamwa kumabweretsa kuchepa kwa 30% kwa kugaya chakudya, ndipo kugaya zakudya m'thupi mwa ana a nkhumba omwe asiya kuyamwa kumachepa kwambiri akakhala ndi vuto lotsegula m'mimba. Kafukufuku wasonyeza kutikutikuwonjezera kuchuluka kwazinki okusayidikudya zakudya zina kungathandize kuwonjezera kuchuluka kwa zinc m'magazi, kuwongolera kwambiri kutulutsa kwa ma peptides a m'matumbo a ubongo ndi mahomoni a njalandikulimbikitsa ana a nkhumba kudya. Nthawi yomweyo, kuchuluka kwa zinc m'magazichitsulokulimbikitsa bwino kapangidwe ndi kuyambitsa kwa ma enzymes am'mimba, kumawonjezera kugayika kwa michere m'thupindionjezerani kulemera kwa ana a nkhumba tsiku ndi tsiku.

Chithunzi 5Zotsatira za zinc oxide pa kukula kwa ana a nkhumba olekanitsidwa

IV. Ndondomeko Yogwiritsira Ntchito Sayansi ndi Zodzitetezera

1. Mlingo wolondola ndi kagwiritsidwe ntchito kake

Ngakhale kuti pali zinc yambiri (1600-2500 mg/kg)zinki okusayidi) chakudya chingagwiritsidwe ntchito kokha mu"masabata awiri oyamba mutatha kuyamwa", minda yambiri ya nkhumba imawonjezera kugwiritsa ntchito chakudya cha zinc chochuluka kwa milungu iwiri mpaka isanu ndi itatu. Pakadali pano, minda ina ya nkhumba idzakumana ndi izi"zotsatirapo zoyipa za zinc", zomwe nthawi zambiri zimaonekera ngati tsitsi lokhuthala komanso lalitali komanso khungu losawoneka bwino.

2. Sankhanizinki okusayidindi kukhazikika kwakukulu kuti zinthu ziyende bwino

Kupezeka kwa bioavailability kwazinki okusayidizomwe zimapangidwa ndi njira yonyowa zimakhala zazikulu kwambiri kuposa zomwe zimapangidwa ndizinki okusayidizopangidwa ndi njira yolunjika. Chifukwa chake, posankhazinki okusayidizinthu, njira yake yopangira iyeneranso kuganiziridwa.

5. Zochitika Zamakampani ndi Chiyembekezo Chaukadaulo Wachilendo

Ngakhale kuti EU yachepetsa kuchuluka kwa zinc yomwe yawonjezeredwa kufika pa 150 mg/kg, machitidwe apakhomo akuwonetsa kuti kusintha kwathunthu zinc yambiri kukukumana ndi zovuta zaukadaulo. Njira zina zamakono monga nano zinc ndi zina zomwe zimagwiritsidwa ntchito popanga zinc.zinki okusayidi(300 mg/kg) ndi zinc chloride yoyambira (1200 mg/kg) zimatha kuchepetsa mlingo, koma mtengo wake ndi wokwera, kukhazikika kwa njira sikokwanira, ndipo chitetezo cha nthawi yayitali chikufunikabe kutsimikiziridwa. Chifukwa chake,wambazinki okusayidiikadali chisankho chabwino kwambiri kwa minda yaing'ono ndi yapakatikati kuti igwirizane ndi mtengo ndi zotsatira zake.