Kugwiritsa Ntchito Hydroxy Methionine Copper 1

Mapulogalamu Ogulitsa

1) Nkhuku za nkhuku

Pamene ma MMHAC (hydroxy methionine chelates ya mkuwaZakudya za nkhuku (zinc, ndi manganese) zinawonjezeredwa ku zakudya za nkhuku, zotsatira zake zinasonyeza kuti—poyerekeza ndi mchere wamba wosakanizidwa—kuphatikizidwa kwa MMHACs kunawonjezera kwambiri kulemera kwa thupi ndi minofu ya ntchafu, kunapangitsa kuti mkuwa usagaye bwino, ndipo sikunakhudze thanzi la gizzard kapena mafupa.

Gome 1. Kulemera kwa nyama yokonzedwa (g/mbalame) ndi bere loyera la matabwa ndi bere la nkhuku zodyetsedwa inorganic ndi methionine hydroxyl analogue chelated zinc, copper, ndi manganese dietary treat sat day 42.

Chinthu	ITM	M10	T125	M30	SEM	Mtengo wa P
Chifuwa	684	716	719	713	14.86	0.415
Ntchafu	397	413	412	425	7.29	0.078
Ndodo ya ng'oma	320	335	332	340	4.68	0.058
Chiuno ndi ndodo ya ng'oma	717 a	748 ab	745 ab	765 b	11.32	0.050
Pedi yamafuta	32.3	33.1	33.4	35.5	1.59	0.546
Chiwindi	68.0	67.4	66.0	71.1	2.41	0.528
Mtima	18.8	18.6	19.2	19.2	0.68	0.898
Impso	9.49	10.2	10.6	10.6	0.51	0.413

Zindikirani: ITM: Mineral yosafunikira ya Inorganic 110 ppm Zn as ZnSO4 16 ppm Cu as CuSO4 ndi120 ppm Mn as MnO pa Ross 308 malangizo azakudya;

M10: Kuchuluka kwa 40 ppm Zn 10 ppm Cu ndi 40 ppm Mn monga chelate;

T125: Mineral yosafunikira ya inorganic 110 ppm Zn monga ZnSO4 ndi 120 ppm Mn monga MnO pa Ross 308 malangizo okhala ndi 125 ppm Cu monga tribasic copper chloride (TBCC);

M30 = 40 ppm Zn, 30 ppm Cu, ndi 40 ppm Mn ngati chelate. Mitengo yomwe ili mu mzere womwewo yokhala ndi ma superscript osiyanasiyana imasiyana kwambiri (P < 0.05).

2) Nkhumba

Kafukufuku adafufuza zotsatira za kusintha pang'ono kwa michere yosafunikira ndi mineral methionine hydroxy analogue chelates (MMHAC) m'zakudya za nkhumba pa nkhumba zonse ziwiri ndi ana awo a nkhumba. Zotsatira zake zidawonetsa kuti kuwonjezera kwa MMHAC kumachepetsa kuchepa kwa thupi m'thupi mwa nkhumba zoyamwitsa, kukulitsa kulemera kwa thupi la nkhumba pa tsiku la 18, kukulitsa kwambiri kuchuluka kwa acetylation ya minofu ya mafupa pobadwa, ndikuchepetsa kufotokozedwa kwa majini ambiri okhudzana ndi kutupa ndi kukula kwa minofu. Ponseponse, MMHAC idasintha thanzi la m'mimba ndi kukula kwa minofu mwa ana a nkhumba kudzera mu epigenetic ndi kasamalidwe ka chitukuko, ndikuwonjezera kuthekera kwawo kukula.

Gome 2 Zotsatira zowonjezera za mineral methionine hydroxy analogue chelate mu zakudya za nkhumba pakuwonetsa kwa key mRNA yokhudzana ndi kutupa kwa jejunal mu mwana wa nkhumba woyamwitsa

Chinthu	ITM	CTM	SEM	P- mtengo
d 1 ya mkaka wa m'mawere x 10^-5
IL-8	1344	1018	178	0.193
MUC2	5380	5511	984	0.925
NF-κB (p50)	701	693	93	0.944
NF-κB (p105)	1991	1646	211	0.274
TGF-b1	Kuyambira mu 1991	1600	370	0.500
TNF-α	11	7	2	0.174
d 18 ya kuyamwitsa x 10^-5
IL-8	1134	787	220	0.262
MUC2	5773	3871	722	0.077

Chidziwitso: Interleukin-8 (IL-8), mucin-2 (MUC2), nuclear factor-κB (NF-κB), transforming growth factor-1 (TGF-1), ndi tumor necrosis factor-α (TNF-α)

ITM = magwero achibadwa a michere yochepa (0.2% ya zomwe zimaphatikizidwa muzakudya)

CTM = 50:50 mineral methionine hydroxy analogue chelate ndi inorganic minerals (0.2% kuphatikizidwa mu zakudya)

3)Nyama zoweta

Mu ng'ombe zoyamwitsa mkaka, m'malo mwa theka la copper sulfate ndihydroxy methionine mkuwaKuchulukitsa kwambiri kuchuluka kwa mkuwa m'magazi, kukweza kugayika kwa ulusi wotsukira wopanda mafuta (NDF) ndi ulusi wotsukira wa acid (ADF), komanso kukulitsa mkaka ndi kupanga mkaka wokonzedwa ndi mafuta ndi 4%. Zomwe zapezekazi zikusonyeza kuti kusintha pang'ono mkuwa wa sulfate ndi (HMTBA)₂-Cu m'zakudya za ng'ombe za mkaka ndi njira yothandiza kwambiri yopezera zakudya.

Gome 3 Zotsatira za methionine hydroxy Cu [(HMTBA)2-Cu] pa kapangidwe ka mkaka wa ng'ombe

Chinthu	S	SM	M	SEM	P-value
DMI, kg/tsiku	19.2	20.3	19.8	0.35	0.23
Kuchuluka kwa mkaka, kg/tsiku	28.8	33.8	31.3	1.06	0.08
Mafuta, %	3.81	3.74	3.75	0.06	0.81
Mapuloteni, %	3.34	3.28	3.28	0.04	0.19
Lactose, %	4.48	4.35	4.43	0.05	0.08
SNF, %	8.63	8.84	8.63	0.05	0.33
Kuchuluka kwa mafuta, kg/tsiku	1.04	1.22	1.10	0.04	0.09
Kuchuluka kwa mapuloteni, kg/tsiku	0.92	0.92	0.90	0.03	0.72
Kuchuluka kwa lactose, kg/tsiku	1.23	1.23	1.21	0.04	0.45
Urea N, mg/dL	18.39	17.70	18.83	0.45	0.19
4% FCM, kg/tsiku	26.1	30.1	27.5	0.91	0.06

Mankhwala: S = Cu sulfate yokha: 12 mg ya Cu yoperekedwa ndi CuSO4 pa kilogalamu imodzi ya concentrate; SM = Cu sulfate ndi (HMTBA)2-Cu: 6 mg ya Cu yoperekedwa ndi CuSO4, ndi 6 mg ina ya Cu yoperekedwa ndi (HMTBA)2-Cu pa kilogalamu imodzi ya concentrate; M = (HMTBA)2-Cu yokha: 12 mg ya Cu yoperekedwa ndi (HMTBA)2-Cu pa kilogalamu imodzi ya concentrate.