Kugwiritsa ntchito Ordinary Zinc Oxid mu Anti-kutsekula m'mimba kwa ana a nkhumba

III. Zovuta za matenda otsekula m'mimba mwa ana oyamwitsa a nkhumba komanso kufunika kwachipatalazinc oxide

Kuyamwitsa ndi vuto lalikulu m'moyo wa nkhumba. Mavuto monga kufooka kwa matumbo otchinga m'matumbo, kusakwanira kwa ma enzymes am'mimba, komanso kusalinganika kwa zomera nthawi zambiri kumayambitsa matenda otsekula m'mimba (PWD), omwe amawopseza kwambiri kukula komanso kuswana kwa ana a nkhumba. Kuyambira wambazinc oxideadapezeka kuti ali ndi zotsatira zotsutsana ndi kutsekula m'mimba m'zaka za m'ma 1980, wakhala "muyezo wagolide" kuti malonda a ziweto padziko lonse athe kuthana ndi PWD. Kafukufuku wasonyeza kuti kuwonjezera 2500-3000 mg/kgzinc oxideamatha kuchepetsa kutsekula m'mimba ndi 40% -60%, ndikuwonjezera kulemera kwa tsiku ndi tsiku ndi 10% -15%. Phindu lake lalikulu lagona pakukhazikitsa matumbo mwachangu kudzera munjira zingapo, kupereka chitetezo chofunikira chosinthira ana a nkhumba.

IV.Mchitidwe wa zochita zazinc oxidemotsutsana ndi kutsekula m'mimba

1)Kulimbikitsa matumbo chotchinga chakuthupi

Zinc oxideimathandizira kuchulukana kwa ma cell a epithelial m'matumbo, imawonjezera kuchuluka kwa kutalika kwa matumbo a villus mpaka kuya kwa crypt, imapangitsa kuti pakhale mayamwidwe a michere, ndipo nthawi yomweyo imayang'anira mawonekedwe a mapuloteni ophatikizika (Occludin, ZO-1), amachepetsa kutsekeka kwamatumbo am'mimba, komanso kutsekereza matumbo. Amateteza matumbo a mucosal chotchinga ntchito, amathandizira antibacterial mphamvu ya ana a nkhumba, komanso amachepetsa kutsekula m'mimba.

Chithunzi 2Zotsatira zosiyanasiyana Mlingo wazinc oxidepa matumbo morphology a nkhumba

Chithunzi 3Zotsatira zosiyanasiyana Mlingo wazinc oxidepa matumbo olimba kwambiri mapuloteni mu ana a nkhumba

2)Kuwongolera m'matumbo microbial balance

Zinc oxideimapanga ma free radicals a hydrogen peroxide m'matumbo, omwe ndi chinthu chofunikira kwambiri pakuchita kwa antibacterial.zinc oxide. Mlingo wambirizinc oxideimalepheretsa mwachindunji kuchuluka kwa mabakiteriya owopsa monga Escherichia coli ndi Salmonella mwa kutulutsa mitundu ya okosijeni yokhazikika (ROS), pomwe ikulimbikitsa kukhazikitsidwa kwa mabakiteriya opindulitsa monga Lactobacillus.

Chithunzi 4Zotsatira za zakudyazinc oxidepa tizilombo ta cecal mu ana a nkhumba

3) Zinc wambiri amalimbikitsa kukula kwa ana a nkhumba

Kupsinjika kwa kuyamwa kumayambitsa kuchepa kwa 30% kwa chakudya cham'mimba, ndipo kagayidwe ka zakudya m’mwana wa nkhumba oyamwa kumacheperachepera pamene akutsekula m’mimba. Kafukufuku wasonyezakutikuwonjezera mlingo waukulu wazinc oxidekwa zakudya akhoza kuonjezera nthaka mlingo mu magazi, kuwongoleranso katulutsidwe ka ma peptides a muubongo ndi mahomoni anjala,ndilimbikitsa ana a nkhumba kudya. Nthawi yomweyo, kuchuluka kwa zinc m'magaziakhozabwino kulimbikitsa kaphatikizidwe ndi kutsegula kwa michere m'mimba, kusintha digestibility wa zakudya,ndikuonjezera kulemera kwa tsiku ndi tsiku kwa ana a nkhumba.

Chithunzi 5Zotsatira za zinc oxide pakukula kwa ana a nkhumba oyamwitsidwa

IV. Ndondomeko Yogwiritsira Ntchito Sayansi ndi Kusamala

1. Mlingo wolondola komanso kagwiritsidwe ntchito kake

Ngakhale zimanenedwa kuti zinc yapamwamba (1600-2500 mg / kgzinc oxide) chakudya chingagwiritsidwe ntchito mu”milungu iwiri yoyambirira mutasiya kuyamwa”, minda yambiri ya nkhumba imakulitsa kugwiritsa ntchito chakudya chambiri cha zinc kwa masabata 2-8. Panthawiyi, minda ina ya nkhumba idzakumana”mkulu zinc zotsatira”, omwe amawoneka ngati tsitsi lalitali komanso lalitali komanso khungu losawoneka bwino.

2. Sankhanizinc oxidendi kukhazikika kwakukulu kuti muwonjezere zotsatira za mankhwala

The bioavailability wazinc oxideopangidwa ndi chonyowa ndondomeko kwambiri apamwamba kuposa wazinc oxideopangidwa ndi ndondomeko yachindunji. Choncho, posankhazinc oxidemankhwala, ndondomeko yake yopanga iyeneranso kuganiziridwa.

5. Zochitika Zamakampani ndi Njira Zamakono Zamakono

Ngakhale kuti EU yachepetsa kuchuluka kwa zinki zomwe zawonjezeredwa ku 150 mg/kg, zochitika zapakhomo zikuwonetsa kuti kuchotsa kwathunthu zinki kumayang'anizana ndi zovuta zaukadaulo. Njira zina zamakono monga nanozinc oxide(300 mg / kg) ndi maziko a zinc chloride (1200 mg / kg) amatha kuchepetsa mlingo, koma mtengo wawo ndi wokwera, kukhazikika kwa ndondomeko sikukwanira, ndipo chitetezo cha nthawi yayitali chiyenera kutsimikiziridwa. Chifukwa chake,wambazinc oxideakadali chisankho chabwino kwambiri kwa mafamu ang'onoang'ono ndi apakatikati kuti athe kulinganiza mtengo ndi zotsatira zake.

Wambazinc oxide

Mbadwo woyamba wa Sustarzinc oxide

Chiyero chachikulu + chapamwamba + mtengo wotsika = zabwino zitatu mu chimodzi

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